"what would happen if you took the brain from a newborn human, who hasn't yet learned to control its human body, and put it into a machine. It would learn about the world solely from it's man-made machine sensors. Communicate with its output and motor devices. Would such a creature be human at all, or an actual sentient machine?" -PJ
First of all, the brain would die because it wouldn't be oxygenated from the perfusion it normally receives with an intact circulatory system attached to a pumping live heart and an actively expanding and deflating lung which takes care of the gas exchange all needed by the brain. Besides, a newborn human brain takes about 2 more years to mature in a process called myelinization before it could be fully functional. So it's not that simple. Detaching the brain from the skull would rip apart the cranial nerves needed for appreciation of much of the sensory input already built-in for the brain (hearing , seeing,smelling, tasting, feeling in the facial area, etc.), as well as some motor nerves for eye movements, swallowing, respiration and heart conduction.
If you took the entire mature head from the lower neck level, leave its vascular attachments to a heart-lung machine and a dialysis machine, it could be a possibility to build robotic attachments, but a difficult one.